Biofutures International plc - Holding(s) in Company

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial
instrument

Exercise
price

Expiration
date

Exercise/
Conversion
period

Number of voting
rights instrument
refers to

% of voting rights

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARES

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

BIOFUTURES INTERNATIONAL PLC

2 Reason for the notification (please tick the appropriate box or boxes):
An acquisition or disposal of voting rights		ü
An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached
An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments
An event changing the breakdown of voting rights
Other (please specify):

3. Full name of person(s) subject to the notification obligation:

Gartmore Investment Limited

4. Full name of shareholder(s) (if different from 3.):

See attached Schedule

5. Date of the transaction and date on which the threshold is crossed or reached:

22 March 2010

6. Date on which issuer notified:

23 March 2010

7. Threshold(s) that is/are crossed or reached:

10%

8. Notified details:
A: Voting rights attached to shares
Class/type of shares if possible using the ISIN CODE	Situation previous to the triggering transaction		Resulting situation after the triggering transaction
	Number of Shares	Number of Voting Rights	Number of shares	Number of voting rights		% of voting rights
			Direct	Direct	Indirect	Direct	Indirect
ORDINARY GB00B12B4T47	10,975,000	10,975,000	15,934,030	-	15,934,030	-	10.548%

B: Qualifying Financial Instruments
Resulting situation after the triggering transaction
Type of financial instrument	Expiration date	Exercise/ Conversion Period	Number of voting rights that may be acquired if the instrument is exercised/ converted.	% of voting rights

Total (A+B+C)

Number of voting rights

Percentage of voting rights

15,934,030

10.548%

9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:

Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

All figures are based on the Company's issued share capital of 151,060,000 as provided by Exshare

14. Contact name:

RDU

15. Contact telephone number:

0207 782 2324

For further information contact:

JULIE POMEROY, FINANCE DIRECTOR, BIOFUTURES INTERNATIONAL PLC - 07747 624 199

DEREK CROWHURST, RELIGARE CAPITAL MARKETS (NOMAD) - 0207 444 0800

DANIEL BRIGGS, RELIGARE CAPITAL MARKETS (BROKER) - 0207 444 0500

Schedule

Fund Managing Company	UK Registered Owner	Beneficial Owner	% of Issued Share Capital	Shares Held
Gartmore Fund Managers Limited	HSBC Global Custody Nominee UK Ltd	Gartmore Fund Managers Ltd A/C Gartmore UK & Irish Smaller Companies	4,375,000	2.896%
Gartmore Investment Limited	Nortrust Nominees Limited	Strathclyde Pension Fund	4,550,000	3.012%
	Gartmore Growth Opportunities	Gartmore Growth Opportunities Plc	1,034,030	0.685%
	Vidacos Nominees Ltd A/C 2303	The Alphagen Volantis Fund Limited	5,975,000	3.955%
Total			15,934,030	10.548%